Information Obtained from Chorionic Villus Sampling (CVS)
The main purpose of Chorionic Villus Sampling (CVS) is to collect a small sample of cells from the placenta, known as chorionic villi. These cells contain genetic material that can be analysed to obtain important information about the baby’s health and genetic makeup.
Through CVS, doctors can identify:
Chromosomal Abnormalities:
CVS is highly effective in detecting chromosomal conditions such as Down syndrome (Trisomy 21), Edwards syndrome (Trisomy 18), and Patau syndrome (Trisomy 13).
Genetic Disorders:
The test can also identify inherited genetic conditions, especially when there is a known family history or when parents are carriers of specific genetic disorders.
When is CVS Recommended?
CVS may be recommended in certain situations where there is an increased risk of genetic or chromosomal abnormalities, including:
Advanced Maternal Age:
Women aged 35 years or older have a higher risk of chromosomal abnormalities in their babies. CVS may be advised to assess fetal chromosomes.
Abnormal Prenatal Screening Results:
If early prenatal screening tests, such as first-trimester screening, indicate potential genetic concerns, CVS may be recommended for further confirmation.
Family History of Genetic Conditions:
When a family has a known history of genetic disorders or chromosomal abnormalities, CVS can provide more detailed information about the fetus.
Previous Child with Genetic Disorders:
Couples who previously had a child with a chromosomal abnormality may choose CVS in future pregnancies to assess potential genetic risks.
Abnormal Ultrasound Findings:
If structural abnormalities or growth concerns are identified during an ultrasound, CVS may be recommended to obtain additional genetic information.
Differences Between Amniocentesis and Chorionic Villus Sampling
Both amniocentesis and CVS are prenatal diagnostic tests used to detect genetic abnormalities. However, they differ in several aspects, including timing, sample type, and procedure.
Timing of the Procedure
Amniocentesis:
Usually performed between the 15th and 20th weeks of pregnancy.
CVS:
Typically conducted earlier, between the 10th and 13th weeks of pregnancy.
Sample Collection
Amniocentesis:
A small amount of amniotic fluid is withdrawn from the amniotic sac surrounding the fetus.
CVS:
A small sample of chorionic villi is collected from the placenta.
Type of Cells Analyzed
Amniocentesis:
Analyses fetal cells present in the amniotic fluid, which originate from the baby’s skin, urinary system, and digestive tract.
CVS:
Examines placental cells from the chorionic villi, which reflect the baby’s genetic makeup.
Genetic Information Obtained
Both tests can detect chromosomal abnormalities such as Down syndrome, Edwards syndrome, and Patau syndrome. They can also identify certain inherited genetic disorders when there is a known family history or carrier status.
Risk of Miscarriage
Amniocentesis:
Generally carries a lower risk of miscarriage, estimated at approximately 1 in 300 to 1 in 500 procedures.
CVS:
Traditionally associated with a slightly higher miscarriage risk, estimated at around 1 in 100 to 1 in 200 procedures.
Timing of Results
Amniocentesis:
Test results are usually available within two to three weeks.
CVS:
Results are typically obtained faster, often within one to two weeks.
Procedure Technique
Amniocentesis:
A thin needle is inserted through the abdominal wall into the amniotic sac under ultrasound guidance.
CVS:
The sample may be collected either through the abdomen (transabdominal) or through the cervix (transcervical), depending on placental position and maternal anatomy.
Suitability for Early Detection
Amniocentesis:
May be preferred for certain conditions when more detailed analysis or additional decision-making time is required.
CVS:
Often chosen for earlier diagnosis because it can be performed earlier in pregnancy.
Cradle Fertility’s Approach to CVS
At Cradle Fertility, CVS is performed with a strong focus on accuracy, safety, and patient care. Our goal is to provide expectant parents with reliable genetic information that helps them make informed decisions about their pregnancy.
Our approach includes:
Experienced Medical Specialists:
Highly trained doctors and healthcare professionals perform the procedure with precision and care.
Comprehensive Genetic Counselling:
Patients receive detailed guidance and support before and after the procedure to help them understand the results and available options.
Advanced Technology:
We utilize modern diagnostic tools and state-of-the-art laboratory techniques to ensure accurate genetic analysis.
Personalized Care and Support:
Every patient receives individualized attention and compassionate support throughout the process.
At Cradle Fertility, CVS is more than just a diagnostic procedure. It is part of a comprehensive approach designed to support families with accurate information, expert care, and guidance. By combining advanced technology with compassionate care, we help expectant parents make confident decisions for the health and future of their growing family.